A few days after David Lynch's death, the homage that Giunti Odeon is dedicating to one of the greatest filmmakers in the history of cinema continues with a special screening of one of his masterpieces. Los Angeles: saxophonist Fred Madison is haunted by the dispatch of a series of videotapes recording his life from various points of view. Married to Renée, he attends a party with her where he is approached by a mysterious man who taunts and terrorises him. The next day, Fred receives a VHS in which Renée's butchered body can be seen. Arrested for murder, in prison he suffers excruciating migraines and one morning, in his cell, another man, Pete, a young mechanic who is immediately released, wakes up in his place. In the pay of the underworld, Pete becomes the lover of the boss's girlfriend, Alice, who bears a striking resemblance to Fred's wife. The woman involves Pete in a heist against a porn film director: everything goes wrong, however, and the man enters a realm of madness and mystery...